[{"id":"hgsoc","kind":"term","name":"High-grade serous ovarian carcinoma (HGSOC)","route":"/terms/hgsoc/","commit":"28a6975696","date":"2026-09-10","author":"Jude Gomila","message":"Tone pass: solution and mechanism first; frightening figures behind a click","file":"src/data/spikes/ovarian.ts","type":"changed","fields":[{"field":"tldr","before":"\"High-grade serous ovarian carcinoma is the most common and most lethal type of ovarian cancer; it actually starts in the fallopian tube and almost always has a broken TP53 gene.\"","after":"\"High-grade serous ovarian carcinoma is the most common type of ovarian cancer and the one most often found late; it actually starts in the fallopian tube and almost always has a broken TP53 gene, and it is the type P..."},{"field":"summary","before":"\"About 70% of ovarian cancer deaths. Near-universal TP53 mutation, ~50% homologous recombination deficiency (including ~20% BRCA1/2), extensive copy-number instability, few recurrent targetable mutations. Arises from ...","after":"\"The type behind about 70% of ovarian cancer deaths, and the one where maintenance therapy has changed the most. Near-universal TP53 mutation, ~50% homologous recombination deficiency (including ~20% BRCA1/2), extensi..."}]},{"id":"hgsoc","kind":"term","name":"High-grade serous ovarian carcinoma (HGSOC)","route":"/terms/hgsoc/","commit":"0bdbdae6c6","date":"2026-09-09","author":"Jude Gomila","message":"Editing pass: every TL;DR and summary stands alone","file":"src/data/spikes/ovarian.ts","type":"changed","fields":[{"field":"tldr","before":"\"The most common and most lethal type of ovarian cancer, which actually starts in the fallopian tube and almost always has a broken TP53 gene.\"","after":"\"High-grade serous ovarian carcinoma is the most common and most lethal type of ovarian cancer; it actually starts in the fallopian tube and almost always has a broken TP53 gene.\""}]},{"id":"hgsoc","kind":"term","name":"High-grade serous ovarian carcinoma (HGSOC)","route":"/terms/hgsoc/","commit":"afc6af185b","date":"2026-09-08","author":"Jude Gomila","message":"Spikes: ovarian, endometrial, cervical cancer deep dives (74 new entities with structured outcomes, dosing, toxicity, regulatory events, gui","file":"src/data/spikes/ovarian.ts","type":"added","fields":[{"field":"id"},{"field":"name"},{"field":"category"},{"field":"tldr"},{"field":"summary"},{"field":"cancers"},{"field":"targets"},{"field":"terms"}]}]