[{"id":"medulloblastoma","kind":"cancer","name":"Medulloblastoma","route":"/cancers/medulloblastoma/","commit":"28a6975696","date":"2026-09-10","author":"Jude Gomila","message":"Tone pass: solution and mechanism first; frightening figures behind a click","file":"src/data/spikes/gap-cancers.ts","type":"changed","fields":[{"field":"summary","before":"\"Medulloblastoma is an embryonal tumour of the posterior fossa with four consensus molecular subgroups (WNT, SHH, Group 3, Group 4) that differ in age, genetics, metastatic tendency and survival: WNT (~10%, CTNNB1 mut...","after":"\"Medulloblastoma is an embryonal tumour of the posterior fossa with four consensus molecular subgroups (WNT, SHH, Group 3, Group 4) that differ in age, genetics, metastatic tendency and survival: WNT (~10%, CTNNB1 mut..."},{"field":"openProblems","before":"[\"Group 3 MYC-amplified and SHH TP53-mutant tumours: survival under 50%.\", \"Relapse is almost always fatal after craniospinal irradiation.\", \"Neurocognitive, endocrine and hearing sequelae in survivors.\", \"Infants: cu...","after":"[\"Group 3 MYC-amplified and SHH TP53-mutant tumours: survival under 50%.\", \"Relapse after craniospinal irradiation is rarely curable; it is where new approaches are most needed.\", \"Neurocognitive, endocrine and hearin..."}]},{"id":"medulloblastoma","kind":"cancer","name":"Medulloblastoma","route":"/cancers/medulloblastoma/","commit":"0bdbdae6c6","date":"2026-09-09","author":"Jude Gomila","message":"Editing pass: every TL;DR and summary stands alone","file":"src/data/spikes/gap-cancers.ts","type":"changed","fields":[{"field":"tldr","before":"\"The most common malignant childhood brain tumour, arising in the cerebellum. Surgery, radiation to the whole brain and spine, and chemotherapy cure about 70%, at a heavy cost to thinking and growth; treatment is now ...","after":"\"Medulloblastoma is the most common malignant childhood brain tumour, arising in the cerebellum. Surgery, radiation to the whole brain and spine, and chemotherapy cure about 70%, at a heavy cost to thinking and growth..."}]},{"id":"medulloblastoma","kind":"cancer","name":"Medulloblastoma","route":"/cancers/medulloblastoma/","commit":"71e4eef6e1","date":"2026-09-08","author":"Jude Gomila","message":"Gap audit and gap-fill data: 33 cancers, 87 products, 20 targets, 25 technologies, 12 terms, 18 collections","file":"src/data/spikes/gap-cancers.ts","type":"added","fields":[{"field":"id"},{"field":"name"},{"field":"group"},{"field":"wikipedia"},{"field":"burden"},{"field":"tldr"},{"field":"summary"},{"field":"subtypes"},{"field":"biomarkers"},{"field":"standardOfCare"},{"field":"stateOfArt"},{"field":"history"},{"field":"pipeline"},{"field":"openProblems"},{"field":"targets"},{"field":"technologies"},{"field":"drugs"},{"field":"pathways"},{"field":"companies"},{"field":"institutions"},{"field":"terms"},{"field":"links"},{"field":"tags"}]}]