Rivastigmine
Rivastigmine is used for Alzheimer’s dementia and has a US indication for dementia associated with Parkinson’s disease. It is a symptom treatment.
Overview
Patch and capsules exist. Gastrointestinal effects and patch-site reactions matter in frail people. It is not a disease-modifying Lewy body treatment.
Cholinesterase inhibitor, oral or patch. Connects to Acetylcholinesterase.
1.Rivastigmine slips into a pocket on Acetylcholinesterase.
Approvals
| Region | Year | Indication |
|---|---|---|
| US | 2000 | Alzheimer’s dementia; Parkinson’s disease dementia |
| EU | 1998 | Alzheimer’s dementia |
| UK | 1998 | Alzheimer’s dementia |
| JP | 2011 | Alzheimer’s dementia |
| CN | 2000 | Alzheimer’s dementia |
| AU | 2000 | Alzheimer’s dementia |
Trials
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Latest papers
topQuery for this drug: (TITLE:"Rivastigmine" OR ABSTRACT:"Rivastigmine" OR TITLE:"Exelon" OR ABSTRACT:"Exelon") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Rivastigmine, not a curated reading list.
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