Cholinesterase inhibitors
These older medicines can support cognitive symptoms for some people. They are not disease-modifying.
Overview
Donepezil, rivastigmine, and galantamine are the core examples. Gastrointestinal effects and slow heart rate need review.
- Old, cheap, safe drugs
- Databases and AI ranking
- Randomised trial gives the verdict
- MA.32 metformin: null. Lynch aspirin: works. Add-Aspirin: ongoing
How it works
Increase acetylcholine signalling at synapses.
Latest papers
topQuery for this technology: (TITLE:"Cholinesterase inhibitors" OR ABSTRACT:"Cholinesterase inhibitors") AND (cancer OR tumor OR tumour OR oncology OR carcinoma OR lymphoma OR leukemia OR leukaemia OR myeloma OR sarcoma OR melanoma OR glioma). Results are unfiltered search hits about Cholinesterase inhibitors, not a curated reading list.
Similar pages
not linked directly; found by shared links- TargetAcetylcholinesterase
Shares Donepezil, Galantamine, Rivastigmine, Dementia with Lewy bodies and the tag dementia-atlas.
- DiagnosisParkinson’s disease dementia
Shares Rivastigmine, Dementia with Lewy bodies and the tag dementia-atlas.
- BottleneckWrong-subtype treatment
Shares Dementia with Lewy bodies, Alzheimer’s disease and the tag dementia-atlas.
- TargetAlpha-synuclein
Shares Dementia with Lewy bodies and the tag dementia-atlas.
- PersonAlois Alzheimer
Shares Alzheimer’s disease and the tag dementia-atlas.
- TreatmentBrexpiprazole
Shares Alzheimer’s disease and the tag dementia-atlas.
- CollectionClinicalTrials.gov
Shares Alzheimer’s disease and the tag dementia-atlas.
- TreatmentMemantine
Shares Alzheimer’s disease and the tag dementia-atlas.