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Genetics
Genes can change risk and, rarely, cause familial disease. ApoE ε4 also changes antibody-safety counselling.
Overview
Most dementia is not a single-gene disease. ApoE ε4 is a risk variant used in ARIA counselling, not a destiny. Autosomal-dominant Alzheimer’s disease and some FTD syndromes need genetics counselling, not a casual test.
Genetics: how this front works · animated schematic, not to scale